Carcinoembryonic Antigen and Prognosis in Patients with Colon Cancer

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منابع مشابه

C-stage in colon cancer: implications of carcinoembryonic antigen biomarker in staging, prognosis, and management.

BACKGROUND The American Joint Committee on Cancer (AJCC) has proposed the inclusion of pretreatment serum carcinoembryonic antigen (CEA) level (C-stage) into the conventional TNM staging system of colon cancer. We assessed the prognosis of various stages of colon cancer after such an inclusion. METHODS Data for all patients (N = 17 910) diagnosed with colonic adenocarcinoma (AJCC stages I, II...

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Carcinoembryonic antigen and albumin predict survival in patients with advanced colon and rectal cancer.

HYPOTHESIS Patients with stage IV colon or rectal cancer at initial diagnosis have characteristics that will predict subsequent survival time. DESIGN Retrospective cohort study. SETTING Urban county teaching hospital providing tertiary care. PATIENTS Patients who came to the study institution with stage IV colon or rectal cancer between 1991-1999. MAIN OUTCOME MEASURE Survival duration ...

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The predictive value of preoperative carcinoembryonic antigen level in the prognosis of colon cancer.

BACKGROUND We evaluated factors associated with an increased preoperative carcinoembryonic antigen (CEA) level for colon cancer patients undergoing elective curative surgery and assessed whether this was associated with prognosis when accounting for other potential confounders. METHODS Prospectively accrued data of patients with stage I, II, and III colon cancer undergoing surgery (1980-2008)...

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Serum levels of carcinoembryonic antigen and a tumor-extracted carcinoembryonic antigen-related antigen in cancer patients.

Levels of carcinoembryonic antigen (CEA) and a tumor-extracted CEA-related antigen (TEX) were determined in sera from patients with carcinomas of the breast, colon, lung, head and neck, and a number of miscellaneous categories. The purpose of this study was to compare the levels of each antigen at various stages of malignant disease. Competitive radioimmunoassays developed in our laboratory wer...

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Preoperative carcinoembryonic antigen as an outcome predictor in colon cancer.

OBJECTIVE Several reports have shown that certain pre-operative CEA intervals can be predictive of long-term outcomes and have subsequently implied that preoperative CEA may be useful to assess the risk of recurrence or death as a continuous number for individual cases. This analysis assesses if this hypothesis is valid after correction for confounders. METHODS All colon cancer patients opera...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1975

ISSN: 0003-4932

DOI: 10.1097/00000658-197501000-00017